UWCScholar :: Browsing by Author "Mfeketho, Mziwoxolo"

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A Study on Leadership in the Implementation of Non-Custodial Sentencing by the Department of Justice and Constitutional Development and the Department of Correctional Services
(University of the Western Cape, 2019) Mfeketho, Mziwoxolo; Esau, Michelle
In this study, new solid supramolecular derivatised forms of bis(adamantine-1-aminium) carbonate (ADTCO3) were prepared. ADTCO3 is a derivative of amantadine used for Parkinson’s disease and has antiviral properties against influenza-A, dengue fever and pharmacological activity towards Parkinson’s disease. The new forms prepared were polymorphic and co-crystal forms of ADTCO3. Polymorphism is a phenomenon where the ability of a substance to exist in two or more crystalline forms occurs when crystallised under different conditions and co-crystallization is the process of formation of multicomponent crystals of a drug substance.