Browsing by Author "Harribhai Hitesh Ishwarlal"

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    The effects of water extracts on testosterone production in-vitro
    (University of the Western Cape, 2012) Harribhai Hitesh Ishwarlal; Pool Edmund
    The reproductive success of any species is dependent on the optimal functioning of both the male and female reproductive systems of that species. The male reproductive system is a highly intricate system that works interdependently with the endocrine system to maintain homeostasis. The system not only produces functioning male gametes, but is responsible for producing steroid hormones such as testosterone. The biosynthesis of testosterone involves multiple steps initiated by the stimulation of the Leydig cells in the testes by luteinising hormone. This biosynthetic pathway is highly susceptible to interference by substances mimicking the actions of the intermediate enzymes. These substances are referred to as endocrine disrupting chemicals (EDCs). These EDCs are found in high concentrations in wastewater. The city of Windhoek, Namibia, is an arid city where available surface and ground water resources do not meet domestic and industrial demands. To supplement Windhoek's water supply, the city started reclaiming water from the wastewater generated primarily from domestic sources.