Browsing by Author "Ekpo, Okobi E."

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    Neuroprotective activities of Boophone haemanthoides (amaryllidaceae) extract and its chemical constituents
    (Multidisciplinary Digital Publishing Institute (MDPI), 2020) Ibrakaw, Abobaker S.; Omoruyi, Sylvester I.; Ekpo, Okobi E.
    Parkinson’s disease (PD) is a neurodegenerative condition that progresses as age increases, and some of its major symptoms include tremor and postural and movement-related difficulties. To date, the treatment of PD remains a challenge because available drugs only treat the symptoms of the disease or possess serious side effects. In light of this, new treatment options are needed; hence, this study investigates the neuroprotective effects of an organic Boophone haemanthoides extract (BHE) and its bioactive compounds using an in vitro model of PD involving the toxin 1-methyl-4-phenylpyridinium (MPP+) and SH-SY5Y neuroblastoma cells.