Browsing by Author "Duvenage, Eugene"
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Item miRNAMatcher: High throughput miRNA discovery using regular expressions obtained via a genetic algorithm(University of the Western Cape, 2008) Duvenage, Eugene; Bajic, Vladimir; Faculty of ScienceIn summary there currently exist techniques to discover miRNA however both require many calculations to be performed during the identification limiting their use at a genomic level. Machine learning techniques are currently providing the best results by combining a number of calculated and statistically derived features to identify miRNA candidates, however almost all of these still include computationally intensive secondary-structure calculations. It is the aim of this project to produce a miRNA identification process that minimises and simplifies the number of computational elements required during the identification process.