Browsing by Author "De Bruin, Franklin Quelain"

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    Advancement in electrochemical sensing of chloramphenicol in varying matrixes: a review
    (Elsevier B.V., 2025) Mulaudji, Kgwadu Percy; Mokwebo, Kefilwe Vanessa; De Bruin, Franklin Quelain; Pokpas, Keagan; Ross, Natasha
    Chloramphenicol (CAP) have demonstrated its broad effectiveness against bacterial infections. However, its persistence in the environment and potential toxicity led to strict global regulations limiting its use. As a result, rapid and accurate detection methods for CAP are being developed to protect public health and maintain regulatory compliance regarding its presence in the environment. Conventional analytical methods such as High-Performance Liquid Chromatography, Gas Chromatography, and Liquid Chromatography–Mass Spectrometry were commonly used for CAP detection. However, these conventional methods suffer challenges such as time-consumption, fabrication complexity, reproducibility, and cost. With electrochemical sensing techniques presenting varying valuable benefits, such as instant detection, low power consumption, simultaneous analysis, and portability, making them essential for timely monitoring of various analytes. The performance of electrochemical sensor is further boosted by integrating materials such as spinels, metal oxides, and metallic nanoparticles. These materials are broadly investigated as electrode interface components thanks to their features that collectively boost electrochemical sensor such as providing excellent electrical conductivity, distinct catalytic behavior, and larger surface areas. Furthermore, this paper reviews the impact of traditional and standards analytical methods, as well as their recent advancement based on the detection of CAP in aqueous media.
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    Carbon-carbon coupling reactions catalysed by palladium nanoparticles supported on the green alga Ulva armoricana
    (University of Western Cape, 2018) De Bruin, Franklin Quelain; Antunes, Edith
    The synthesis of nanomaterials, especially metallic nanoparticles, has attracted an enormous amount of interest over the past decade. They exhibit unique properties that allow the multiple applications in a variety of fields in science and technology. Their applications are limited by the efficiency and control of their synthesis to produce nanoparticles of certain size and shape. With ever mounting concern for the environment, a great amount of research has recently been extended to synthetic procedures that are carried out with limited or no toxicity to human health and the environment. One method involves the use of biological (or biogenic) materials for nanoparticle synthesis. This method is particularly attractive due to the fact that it is a relatively cheap, simple and environmentally friendly method compared to that of conventional chemical methods of synthesis.