Browsing by Author "Christoffels, Alan G."

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    Careful governance of African biobanks
    (Elsevier, 2020) Christoffels, Alan G.; Abayomi, Akin
    The Sydney Statement is one of the first framing documents on the principles for guiding global health security. Framing matters because the funding pool for development assistance for health is finite and has plateaued over the past decade.2,3 Investments in global health security to prevent future catastrophes are subject to competing health priorities, such as scaling up the “most essential interventions” against ongoing epidemics of preventable morbidity and mortality in mothers, infants, and children in the Global South.4 Development assistance for health that prioritises global health security could overwhelm or detract attention from multiple competing health priorities.3
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    COMBAT-TB-NeoDB: Fostering tuberculosis research through integrative analysis using graph database technologies
    (Oxford University Press, 2020) Lose, Thoba; van Heusden, Peter A.; Christoffels, Alan G.
    Tuberculosis (TB) is a significant global health threat, with onethird of the population infected with its causative agent Mycobacterium tuberculosis (M.tb). Globally, researchers have been responding with a plethora of heterogeneous TB databases with each focusing on different subsets of TB data and present limited options for data integration thus impeding the chances of integrative analysis. Although each database can provide answers to certain questions in its scope, it falls short in answering questions that require federated queries across multiple domains of biological knowledge.