Browsing by Author "Bhana, Arvin"

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    Addressing the tensions and complexities involved in commissioning and undertaking implementation research in low- and middle-income countries
    (BMJ, 2018) Doherty, Tanya; Lewin, Simon; Kinney, Mary; Sanders, David; Mathews, Cathy; Daviaud, Emmanuelle; Goga, Ameena; Bhana, Arvin; Besada, Donela; Vanleeuw, Lieve; Loveday, Marian; Odendaal, Willem; Leon, Natalie
    Rapid scale-up of new policies and guidelines, in the context of weak health systems in low/middle-income countries (LMIC), has led to greater interest and funding for implementation research. Implementation research in LMICs is often commissioned by institutions from high-income countries but increasingly undertaken by LMIC-based research institutions. Commissioned implementation research to evaluate large-scale, donor-funded health interventions in LMICs may hold tensions with respect to the interests of the researchers, the commissioning agency, implementers and the country government. We propose key questions that could help researchers navigate and minimise the potential conflicts of commissioned implementation research in an LMIC setting.
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    Task-sharing of psychological treatment for antenatal depression in Khayelitsha, South Africa: Effects on antenatal and postnatal outcomes in an individual randomised controlled trial
    (Elsevier, 2020) Lund, Crick; Schneider, Marguerite; Garman, Emily C; Davies, Thandi; Munodawafa, Memory; Honikman, Simone; Bhana, Arvin; Bassf, Judith; Bolton, Paul; Dewey, Michael; Joska, John; Kagee, Ashraf; Myer, Landon; Petersen, Inge; Prince, Martin; Stein, Dan J; Tabana, Hanani; Thornicroft, Graham; Tomlinson, Mark; Hanlon, Charlotte; Alem, Atalay; Susser, Ezra
    The study's objective was to determine the effectiveness of a task-sharing psychological treatment for perinatal depression using non-specialist community health workers. A double-blind individual randomised controlled trial was conducted in two antenatal clinics in the peri-urban settlement of Khayelitsha, Cape Town. Adult pregnant women who scored 13 or above on the Edinburgh Postnatal Depression rating Scale (EPDS) were randomised into the intervention arm (structured six-session psychological treatment) or the control arm (routine antenatal health care and three monthly phone calls). The primary outcome was response on the Hamilton Depression Rating Scale (HDRS) at three months postpartum (minimum 40% score reduction from baseline) among participants who did not experience pregnancy or infant loss (modified intention-to-treat population) (registered on Clinical Trials: NCT01977326).