Magister Scientiae - MSc (Pharmacy Administration and Policy Regulation)

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Browsing by Author "Butler, Nadine"

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    Awareness regarding non-steroidal anti-inflammatory drug-related side effects in Johannesburg, South Africa
    (University of Western Cape, 2021) Padayachee, Vaneshree; Butler, Nadine
    Non-steroidal anti-inflammatory drugs (NSAIDs) are amongst the most commonly used medications globally, as they are highly effective and easily accessible. The NSAIDs are indicated for mild to moderate pain management. The increasing incidence of NSAID related side effects and hospitalisations has raised a concern about these medications’ safety. The prevalence of these side effects has drastic consequences to a challenged South Africanpublic healthcare system. The implications of not treating severe, potentially preventable upper gastrointestinal complications attributed to NSAIDs’ consumption continue to be a significant problem that healthcare professionals (HCP) face.
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    Pharmacovigilance: An Assessment of Knowledge, Attitude and Practice of Healthcare Professionals towards Adverse Drug Reactions Reporting In Central Region of Malawi
    (University of the Western Cape, 2017) Chulu, Chrissy M.W; Butler, Nadine
    AIM OF THE STUDY: To assess level of knowledge, attitude and practices of dispensing healthcare professionals towards adverse drug reactions (ADR) reporting and to determine if there are any differences in knowledge, attitude and practices among dispensing healthcare professionals METHODOLOGY: A descriptive cross-sectional survey using stratified random sampling technique was employed to draw 114 health facilities using categories of public hospitals, private clinics/hospitals and community pharmacies as strata. Every dispensing healthcare professional found in the main pharmacy of the sampled facilities was targeted. RESULTS: Dispensing healthcare professionals have positive attitude but limited knowledge and poor practice towards ADR reporting. There is significant difference on knowledge towards ADR reporting among healthcare professionals as more of pharmaceutical personnel and medical doctors indicated having knowledge than the other dispensing cadres but there is no significant difference in attitude and practice towards ADR reporting. CONCLUSION: Healthcare professionals in central region of Malawi have limited knowledge and poor practice but positive attitude towards ADR reporting. Lack of training, unavailability of reporting tools and lack of information on how to report has greatly influenced the poor practice of ADR reporting. Educational and awareness interventions on pharmacovigilance, use of appropriately trained personnel and provision of required support to healthcare professionals would greatly improve ADR reporting.