(University of the Western Cape, 2007) Sagar, Sunil.; Green, Ivan R.; Ameer, F.; Dept. of Chemistry; Faculty of Science
Tuberculosis (TB) and Cancer are among the most devastating and therapeutically challenging diseases that need to be addressed in South Africa today. The development of muti-drug resistance in TB causing bacteria, Mycobacterium tuberculosis and cancerous cells has prompted the search for effective novel compounds. The present study focused on the synthesis and the evaluation of different analogues of diospyrin, a proven anti-TB and anti-cancer agent.