Modelling the effect of bednet coverage on malaria transmission in South Sudan

dc.contributor.authorMukhtar, Abdulaziz Y. A.
dc.contributor.authorMunyakazi, Justin B.
dc.contributor.authorOuifki, Rachid
dc.contributor.authorClark, Allan E.
dc.date.accessioned2018-06-13T10:26:00Z
dc.date.available2018-06-13T10:26:00Z
dc.date.issued2018
dc.description.abstractA campaign for malaria control, using Long Lasting Insecticide Nets (LLINs) was launched in South Sudan in 2009. The success of such a campaign often depends upon adequate available resources and reliable surveillance data which help officials understand existing infections. An optimal allocation of resources for malaria control at a sub-national scale is therefore paramount to the success of efforts to reduce malaria prevalence. In this paper, we extend an existing SIR mathematical model to capture the effect of LLINs on malaria trans- mission. Available data on malaria is utilized to determine realistic parameter values of this model using a Bayesian approach via Markov Chain Monte Carlo (MCMC) methods. Then, we explore the parasite prevalence on a continued rollout of LLINs in three different settings in order to create a sub-national projection of malaria. Further, we calculate the model’s basic reproductive number and study its sensitivity to LLINs’ coverage and its efficacy. From the numerical simulation results, we notice a basic reproduction number, R0 , confirming a substantial increase of incidence cases if no form of intervention takes place in the commu- nity. This work indicates that an effective use of LLINs may reduce R0 and hence malaria transmission. We hope that this study will provide a basis for recommending a scaling-up of the entry point of LLINs’ distribution that targets households in areas at risk of malaria.en_US
dc.identifier.citationMukhtar, A.Y.A. et al. (2018). Modelling the effect of bednet coverage on malaria transmission in South Sudan. PLoS ONE 13(6): e0198280.en_US
dc.identifier.issn1932-6203
dc.identifier.urihttps://doi.org/ 10.1371/journal.pone.0198280
dc.identifier.urihttp://hdl.handle.net/10566/3802
dc.language.isoenen_US
dc.privacy.showsubmitterFALSE
dc.publisherPublic Library of Scienceen_US
dc.rightsPLOS one is an open access journal
dc.status.ispeerreviewedFALSE
dc.subjectLong Lasting Insecticide Nets (LLINs)en_US
dc.subjectMalaria controlen_US
dc.subjectResourcesen_US
dc.titleModelling the effect of bednet coverage on malaria transmission in South Sudanen_US
dc.typeArticleen_US

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