Whole-genome sequencing of African swine fever virus from wild boars in the Kaliningrad region reveals unique and distinguishing genomic mutations

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dc.contributor.authorMazloum, Ali
dc.contributor.authorvan Schalkwyk, Antoinette
dc.contributor.authorShotin, Andrey
dc.date.accessioned2023-02-01T09:32:42Z
dc.date.available2023-02-01T09:32:42Z
dc.date.issued2023
dc.description.abstractSince the first report of outbreaks of African swine fever (ASF) in Georgia in 2007, the disease has expanded into Europe, Russia, and Asia, spreading rapidly via contact with infected animals including domestic pigs and wild boars. The vast expansion of this Genotype II African swine fever virus (ASFV) across wide-ranging territories and hosts inevitably led to the acquisition of novel mutations. These mutations could be used to track the molecular epidemiology of ASFV, provided that they are unique to strains restricted within a certain area. Whilst whole-genome sequencing remains the gold standard for examining evolutionary changes, sequencing of a single locus with significant variation and resolution power could be used as a rapid and cost-eective alternative to characterize multiple isolates from a single or related outbrea.en_US
dc.identifier.citationMazloum, A. et al. (2023). Whole-genome sequencing of African swine fever virus from wild boars in the Kaliningrad region reveals unique and distinguishing genomic mutations. Frontiers in Veterinary Science, 9, 1019808. 10.3389/fvets.2022.1019808en_US
dc.identifier.issn2297-1769
dc.identifier.uri10.3389/fvets.2022.1019808
dc.identifier.urihttp://hdl.handle.net/10566/8325
dc.language.isoenen_US
dc.publisherFrontiers Mediaen_US
dc.subjectBiotechnologyen_US
dc.subjectPublic healthen_US
dc.subjectPublic healthen_US
dc.subjectSwine feveren_US
dc.subjectAfricaen_US
dc.titleWhole-genome sequencing of African swine fever virus from wild boars in the Kaliningrad region reveals unique and distinguishing genomic mutationsen_US
dc.typeArticleen_US

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