Evaluation of Antibacterial Activity of Bryopsis pennata and Chaetomorpha antennina against Multidrug Resistant Morganella morganii and Salmonella species Isolated from Healthy Individuals
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Date
2017
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Publisher
International Journal for Pharmaceutical Research Scholars
Abstract
The problem of antibiotic resistance is fast becoming a pandemic which has necessitated the need
for new drugs discovery. This study was carried out to screen two green algal species- Bryopsis
pennata and Chaetomorpha anteninna for antibacterial activity against multidrug resistant
pathogenic enteric organisms (Morganella morganii and Salmonella species) obtained from healthy
individuals. Algal samples were obtained and processed. Crude extraction was carried out with dichloromethane/methanol (2:1) while the antibacterial screening was done by agar-well diffusion
method. Results revealed that M. morganii was 3.37% of the total isolates recovered while
Salmonella species was 6.74%. Result also showed that C. antennina was active against all the
strains of Salmonella species with inhibitory zones ranging from 10 mm to 17 mm and the
M. morganii with inhibitory zone of 11 mm while B. pennata showed inhibitory activities against only
S. pullorum and S. enterica subspecies diarizonae with inhibitory zones of 12 mm and 7 mm
respectively as well as the M. morganii strain with 14 mm. The antibacterial activities observed from
these green algae showed that Bryopsis pennata and Chaetomorpha antennina from the West
African coast are promising in the quest for new drugs with potentials against multidrug resistant
strains of bacteria and therefore should be intensely researched into
Description
Keywords
Bryopsis peƱata, Chaetomorpha antennina, Morganella morganii;, Salmonella species
Citation
Agbaje-Daniels, F. & Babalola, Agape & Akintayo, Ifeoluwa & Adeleye, Adeyemi & Beukes, Denzil & Gudikandula, Krishna. (2017). Evaluation of Antibacterial Activity of Bryopsis pennata and Chaetomorpha antennina against Multidrug Resistant Morganella morganii and Salmonella species Isolated from Healthy Individuals.