Selected antiretroviral and anti-tuberculosis drug combinations by non-covalent bonding
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Date
2021
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
University of Western Cape
Abstract
Treatment of the human immunodeficiency virus (HIV) and tuberculosis (TB) infections have become very complicated due to the advent of drug resistance. Drug combinations offer an alternative approach to reducing the emergence of drug resistance. Pharmaceutical co-crystals have provided the pharmaceutical industry with the ability to optimise the physicochemical properties of active pharmaceutical ingredients (APIs) while preserving the biological activity. Pharmaceutical co-crystals are formed between APIs and suitable co-formers that are biologically safe or even a second or third API.
Description
Doctor Pharmaceuticae - DPharm
Keywords
HIV/AIDS, Tuberculosis, Infectious diseases, Drug resistance, Solid dispersions