Investigating hypoglycaemic effects and safety of the herbal Product – JT2016 in vivo study

dc.contributor.advisorMa, Xuesheng
dc.contributor.authorBrown, Nthabeleng Mary
dc.date.accessioned2022-02-08T13:35:00Z
dc.date.accessioned2024-11-04T13:15:24Z
dc.date.available2022-02-08T13:35:00Z
dc.date.available2024-11-04T13:15:24Z
dc.date.issued2021
dc.descriptionDoctor Educationisen_US
dc.description.abstractDiabetes has since been a global epidemic; an estimated 5.0 million deaths of diabetes in the world have been recorded; one in 11 adults have diabetes (415 million); and by 2040, one adult in 10 (642 million) will have diabetes. In Africa, more than two thirds of people with diabetes are undiagnosed, and 42 million have diabetes in the Sub-Saharan region with 324 877 adult deaths in South Africa (IDF, 2015). The global prevalence (age-standardized) of diabetes has nearly doubled since 1980,rising from 4.7% to 8.5% in the adult population. This reflects an increase associated with risk factors such as overweight or obese (WHO, 2016). Medicinal plants on the other hand, have played a significant role in the treatment and prevention of diabetes for centuries. In South Africa, indigenous medicinal plants have increasingly been used in the treatment of diabetes. In this study, a new anti-diabetes herbal compound named Jiang Tang 2016 (JT2016), made of three well researched South African indigenous medicinal plants is investigated for its hypoglycemic effects in HFD/STZ induced diabetic SD rats. These plants have been used for centuries in the indigenous system of medicine against various ailments, they are easily accessible, they grow in abundance, and are economically sustainable. Aim The aim of this study was to investigate the hypoglycemic effects and safety of the anti- diabetes herbal compound, Jiang Tang 2016 (JT2016) in HFD/STZ induced diabetic SD ratsen_US
dc.identifier.urihttps://hdl.handle.net/10566/17286
dc.language.isoenen_US
dc.publisherUniversity of the Western Capeen_US
dc.rights.holderUniversity of the Western Capeen_US
dc.subjectHyperglycemiaen_US
dc.subjectJiang Tang 2016en_US
dc.subjectDiabetesen_US
dc.subjectBlood glucoseen_US
dc.subjectInsulin Resistanceen_US
dc.titleInvestigating hypoglycaemic effects and safety of the herbal Product – JT2016 in vivo studyen_US

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