Functionalities of electrochemical fluoroquinolone sensors and biosensors

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dc.contributor.authorAjayi, Rachel F.
dc.contributor.authorNepfumbada, Collen
dc.contributor.authorMthombeni, Nomcebo H.
dc.date.accessioned2025-05-05T07:28:23Z
dc.date.available2025-05-05T07:28:23Z
dc.date.issued2023
dc.description.abstractFluoroquinolones (FQs) are a class of broad-spectrum antimicrobial agents that are used to treat variety of infectious diseases. This class of antibiotics was being used for patients exhibiting early symptoms of a human respiratory disease known as the COVID-19 virus. As a result, this outbreak causes an increase in drug-resistant strains and environmental pollution, both of which pose serious threats to biota and human health. Thus, to ensure public health and prevent antimicrobial resistance, it is crucial to develop efective detection methods for FQs determination in water bodies even at trace levels. Due to their characteristics like specifcity, selectivity, sensitivity, and low detection limits, electrochemical biosensors are promising future platforms for quick and on-site monitoring of FQs residues in a variety of samples when compared to conventional detection techniques. Despite their excellent properties, biosensor stability continues to be a problem even today. However, the integration of nanomaterials (NMs) could improve biocompatibility, stability, sensitivity, and speed of response in biosen sors. This review concentrated on recent developments and contemporary methods in FQs biosensors. Furthermore, a variety of modifcation materials on the electrode surface are discussed. We also pay more attention to the practical applications of electrochemical biosensors for FQs detection. In addition, the existing challenges, outlook, and promising future perspec tives in this feld have been proposed. We hope that this review can serve as a bedrock for future researchers and provide new ideas for the development of electrochemical biosensors for antibiotics detection in the future.
dc.identifier.citationNepfumbada, C., Mthombeni, N.H., Sigwadi, R., Ajayi, R.F., Feleni, U. and Mamba, B.B., 2024. Functionalities of electrochemical fluoroquinolone sensors and biosensors. Environmental Science and Pollution Research, 31(3), pp.3394-3412.
dc.identifier.urihttps://doi.org/10.1007/s11356-023-30223-2
dc.identifier.urihttps://hdl.handle.net/10566/20346
dc.language.isoen
dc.publisherSringer
dc.subjectFluoroquinolones
dc.subjectAntibiotics
dc.subjectCOVID-19
dc.subjectBiosensors
dc.subjectDetection
dc.titleFunctionalities of electrochemical fluoroquinolone sensors and biosensors
dc.typeArticle

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