Phenytoin-sodium induced gingival overgrowth

Abstract

Epilepsy is a fairly common condition and the anti-convulsant drug, phenytoin sodium, has been used in its treatment for over 40 years. Shortly after its introduction, the side-effect of gingival overgrowth was re'{XJrted and has been the subject o t of mw h research. Epidemiological studies showed that; gingival overgrowth developed in approximately half the patients treated with this drug, possibly indicating an individual patient susceptibility to this effect of the drug.