The threat of aerobic vaginitis to pregnancy and neonatal morbidity

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dc.contributor.authorKaambo, Eveline
dc.contributor.authorAfrica, Charlene W.J.
dc.date.accessioned2017-08-18T13:59:12Z
dc.date.available2017-08-18T13:59:12Z
dc.date.issued2017
dc.description.abstractAerobic vaginitis (AV) is an endogenous opportunistic infection brought about by the disruption of the normal vaginal microbiota. Its early diagnosis and treatment during pregnancy may reduce the risk of negative pregnancy outcomes. The aim of this review was to report on the aerobic bacteria most prevalent in AV and to provide evidence of the threat of untreated AV on pregnancy outcomes. More than 300 papers on preterm delivery were extracted from several research domains and filtered to include only AV-associated bacteria such as Staphylococcus aureus, Enterococcus faecalis, Escherichia coli and Group B streptococci and their association with adverse pregnancy outcomes. Due to the diverse sample groups, study techniques and outcomes, a meta-analysis was not conducted. The review revealed that the association of AV with adverse pregnancy outcomes has not been as widely researched as bacterial vaginosis (BV) and needs further investigation. Furthermore, the frequent misdiagnosis of AV coupled with the emerging antimicrobial resistance associated with bacteria implicated in AV and neonatal nosocomial infections pose a problem for prophylaxis and treatment to reduce the risk of maternal and neonatal morbidity and mortality.en_US
dc.description.sponsorshipNational Research Foundation (NRF)en_US
dc.identifier.citationKaambo, E. & Africa, C. W. J. (2017). The threat of aerobic vaginitis to pregnancy and neonatal morbidity. African Journal of Reproductive Health, 21(2): 109-118en_US
dc.identifier.issn1118-4841
dc.identifier.urihttp://hdl.handle.net/10566/3138
dc.identifier.urihttps://ajrh.info/index.php/ajrh/article/view/812
dc.language.isoenen_US
dc.publisherWomen's Health and Action Research Centreen_US
dc.rightsThis is the author-version of the article published online at: https://ajrh.info/index.php/ajrh/article/view/812
dc.subjectAerobic vaginitisen_US
dc.subjectPregnancy risksen_US
dc.subjectAntimicrobial resistanceen_US
dc.titleThe threat of aerobic vaginitis to pregnancy and neonatal morbidityen_US
dc.typeArticleen_US

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