Characterisation of human coronavirus-NL63 nucleocapsid protein

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dc.contributor.authorBerry, Michael
dc.contributor.authorManasse, Taryn-Lee
dc.contributor.authorTan, Yee-Joo
dc.contributor.authorFielding, Burtram C.
dc.date.accessioned2013-10-06T20:24:01Z
dc.date.available2013-10-06T20:24:01Z
dc.date.issued2012
dc.description.abstractCoronavirus N is a multifunctional protein that plays an essential role in enhancing the efficiency of virus transcription and assembly. This manuscript reports the analysis of HCoV-NL63 N protein by comparing the amino acid sequences of coronavirus N-homologues. A ~50 kDa protein was expressed in both a mammalian cell and bacterial cell system that is similar in size to the predicted ~42.6 kDa HCoV-NL63 N protein. PSORTII identified two putative nuclear localisations signals and PONDR identified one disordered region in HCoV-NL63 N. The reported protein analysis serves as a prelude to laboratory analysis to understand the processing of HCoV-NL63 N.en_US
dc.description.accreditationWeb of Scienceen_US
dc.identifier.citationBerry, M., et al. (2012). Characterisation of human coronavirus-NL63 nucleocapsid protein. African Journal of Biotechnology, 11(75): 13962-13968en_US
dc.identifier.issn1684–5315
dc.identifier.urihttp://hdl.handle.net/10566/735
dc.language.isoenen_US
dc.privacy.showsubmitterfalse
dc.publisherAcademic Journalsen_US
dc.rights© 2012 Berry, et al; licensee Academic Journals. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by-nc/3.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
dc.source.urihttp://dx.doi.org/10.5897/AJB12.1657
dc.status.ispeerreviewedtrue
dc.subjectHCoV-NL63en_US
dc.subjectNucleocapsid protein
dc.subjectProtein analysis
dc.subjectNuclear localisation signals
dc.subjectProtein ordered/disordered regions
dc.titleCharacterisation of human coronavirus-NL63 nucleocapsid proteinen_US
dc.typeArticleen_US

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