Discovery of antibacterial lead compounds from marine organisms

dc.contributor.advisorBeukes, Denzil R
dc.contributor.advisorTrindade, Marla
dc.contributor.authorAfolayan, Omolola
dc.date.accessioned2021-03-01T13:24:04Z
dc.date.accessioned2024-05-15T07:16:49Z
dc.date.available2024-05-15T07:16:49Z
dc.date.issued2020
dc.descriptionPhilosophiae Doctor - PhDen_US
dc.description.abstractMarine organisms including algae and bacteria are known to produce chemically diverse secondary metabolites for survival purposes in the marine environment. Scientists have identified some of these natural products as therapeutic agents including some antibiotics. Given the increase in the resistance of pathogenic microorganisms especially methicillin-resistant Staphylococcus aureus (MRSA) and Mycobacterium tuberculosis to commonly prescribed antibiotics, researchers have turned towards exploiting marine natural products for new antibacterial compounds. Due to the proven success of finding bioactive compounds in the marine environment this study therefore aims to discover lead compounds against MRSA and Mycobacterium tuberculosis from two marine sources, the marine algae and the bacteria associated with marine invertebrates referred to as bacterial isolates.en_US
dc.description.embargo2024
dc.identifier.urihttps://hdl.handle.net/10566/15052
dc.language.isoenen_US
dc.publisherUniversity of the Western Capeen_US
dc.rights.holderUniversity of the Western Capeen_US
dc.subjectAntibacterialen_US
dc.subjectMarine organismsen_US
dc.subjectNatural productsen_US
dc.subjectAntibioticsen_US
dc.subjectMycobacterium tuberculosisen_US
dc.titleDiscovery of antibacterial lead compounds from marine organismsen_US

Files

Original bundle
Now showing 1 - 1 of 1
Loading...
Thumbnail Image
Name:
ofalayan_phd_nsc_2020_24.pdf
Size:
11.68 MB
Format:
Adobe Portable Document Format
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.71 KB
Format:
Plain Text
Description: