Examination of maternal gingival crevicular fluid for the presence of selected periodontopathogens implicated in the pre-term delivery of low birthweight infants

dc.contributor.authorAfrica, Charlene W.J.
dc.contributor.authorKayitenkore, Janet
dc.contributor.authorBayingana, Claude
dc.date.accessioned2014-01-09T19:23:51Z
dc.date.available2014-01-09T19:23:51Z
dc.date.issued2010
dc.description.abstractBackground: Reports show that more than 20 million infants world-wide are born prematurely with 95% of all pre-term births occurring in developing countries. Oral colonization of Gram-negative anaerobes has been implicated as a risk factor for preterm delivery of low birth weight infants. Results: Association of bacterial species with the risk of periodontal disease and thus the risk of preterm delivery was only observed when they occurred in pairs or groups of three or more. Aa appeared to be a necessary co-factor for significant associations of bacterial groups with the variables recorded. Materials and Methods: This study comprised 200 women admitted to the department of obstetrics and gynecology of the teaching hospital of Butare in Rwanda. Gingival crevicular fluid was collected from each quadrant of the mother’s mouth (using paper points) within 24 hours of delivery. A dichotomous score of presence or absence of gingival inflammation was recorded for each patient along with demographic data such as age, marital status etc. Samples were examined by PC R for the presence of Aggregatibacter actinomycetemcomitans and selected members of the red and orange complexes described by Socransky et al. (1998), and their presence associated with age, gingival inflammation and pregnancy outcomes.en_US
dc.description.accreditationWeb of Scienceen_US
dc.description.sponsorshipNational Research Foundation of South Africaen_US
dc.identifier.citationAfrica, C.W.J. Kayitenkore, J. Bayingana, C. (2010). Examination of maternal gingival crevicular fluid for the presence of selected periodontopathogens implicated in the pre-term delivery of low birthweight infants. Virulence, 1(4):254-259en_US
dc.identifier.issn2150-5594
dc.identifier.urihttp://hdl.handle.net/10566/927
dc.identifier.urihttp://dx.doi.org/10.4161/viru.1.4.12004
dc.language.isoenen_US
dc.privacy.showsubmitterfalse
dc.publisherLandes Bioscienceen_US
dc.rightsThis is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited. Article available online at: http://dx.doi.org/10.4161/viru.1.4.12004
dc.status.ispeerreviewedtrue
dc.subjectPrevalenceen_US
dc.subjectPeriodontopathogensen_US
dc.subjectMaternal gingival crevicular fluiden_US
dc.subjectRwandaen_US
dc.titleExamination of maternal gingival crevicular fluid for the presence of selected periodontopathogens implicated in the pre-term delivery of low birthweight infantsen_US
dc.typeArticleen_US

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