Iterative prophylactic treatment by hematin in two cases of recurrent disabling acute intern1ittent porphyria (AIP)

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dc.contributor.authorMugabo, Pierre
dc.contributor.authorCoche, Lefebvre E.
dc.contributor.authorHassoun, A.
dc.date.accessioned2014-09-03T13:28:42Z
dc.date.available2014-09-03T13:28:42Z
dc.date.issued1989
dc.description.abstractSummary: Hematin is known as a useful drug in the treatment of acute intermittent porphyria (Al P) attacks. We have used it with success as an iterative prophylactic treatment in two cases of AIP with recurrent disabling crises. In one of the two cases, the kinetic study of plasmatic delta amino-fernlinic acid (ALA) has shown an ALA plasma level (40-45 μg/dl) which is considered to be a trigger level for this patient. Cntil now, no side effects due to such a hematin treatment have been observed in either patient. This schedule could represent an improvement in the management of recurrent disabling AI P crises.en_US
dc.description.accreditationWeb of Scienceen_US
dc.identifier.citationMugabo, P., Coche, L.E. & Hassoun, A. (1989). Iterative prophylactic treatment by hematin in two cases of recurrent disabling acute intern1ittent porphyria (AIP). European Journal of Internal Medicine, 1: 153-6en_US
dc.identifier.issn0953-6205
dc.identifier.urihttp://hdl.handle.net/10566/1226
dc.language.isoenen_US
dc.privacy.showsubmitterfalse
dc.publisherElsevieren_US
dc.rights© 1989 Elsevier.
dc.status.ispeerreviewedtrue
dc.subjectHematinen_US
dc.subjectAcute intermittent porphyria (AIP)en_US
dc.subjectIterative prophylactic treatmenten_US
dc.titleIterative prophylactic treatment by hematin in two cases of recurrent disabling acute intern1ittent porphyria (AIP)en_US
dc.typeArticleen_US

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Prof. Pierre Mugabo