Biological synthesis of gold and silver nanoparticles using leaf extracts of Crassocephalum rubens and their comparative in vitro antioxidant activities

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dc.contributor.authorAdewale, Olusola B.
dc.contributor.authorEgbeyemi, Kayode A.
dc.contributor.authorFadaka, Adewale O.
dc.date.accessioned2022-06-13T09:08:29Z
dc.date.available2022-06-13T09:08:29Z
dc.date.issued2020
dc.description.abstractThe use of plant and plant products in the synthesis of silver nanoparticles (AgNPs) and gold nanoparticles (AuNPs) is made possible because of the natural inherent phytochemicals responsible for the reduction of respective metallic salts to nanoparticle forms, and ensuring therapeutic applicability. In this study, synthesis of AgNPs and AuNPs was performed using two different aqueous extraction methods for Crassocephalum rubens: maceration using laboratory method of extraction (cold aqueous extract of Crassocephalum rubens (AECR)), and decoction using traditional healer's method of extraction (hot aqueous crude extract of Crassocephalum rubens (CECR)). The synthesized nanoparticles were characterized using various methods, and in vitro antioxidant po- tential were thereafter investigated. The characterization results indicated the formation of mostly spherical- shaped AgNPs and AuNPs with surface plasmon resonance (SPR) band of 470 nm and 540 nm, respectively. The nanoparticles possess high antioxidant potentials but AECR synthesized AuNPs exhibited the least phyto- chemical contents and antioxidant potential when compared to other nanoparticles. It can therefore be concluded that extraction method and nanoparticle type are important factors that could influence the antioxidant properties of the nanoparticles. Further studies using these nanoparticles as anticancer or anti-inflammatory agent in both in vitro and in vivo are underway.en_US
dc.identifier.citationAdewale, O. B. et al. (2020). Biological synthesis of gold and silver nanoparticles using leaf extracts of Crassocephalum rubens and their comparative in vitro antioxidant activities. Heliyon, 6(11), e05501. https://doi.org/10.1016/j.heliyon.2020.e05501en_US
dc.identifier.issn2405-8440
dc.identifier.urihttps://doi.org/10.1016/j.heliyon.2020.e05501
dc.identifier.urihttp://hdl.handle.net/10566/7510
dc.language.isoenen_US
dc.publisherElsevieren_US
dc.subjectMaterials scienceen_US
dc.subjectNanotechnologyen_US
dc.subjectAntioxidanten_US
dc.subjectCrassocephalum rubensen_US
dc.subjectGold nanoparticlesen_US
dc.subjectSilver nanoparticlesen_US
dc.titleBiological synthesis of gold and silver nanoparticles using leaf extracts of Crassocephalum rubens and their comparative in vitro antioxidant activitiesen_US
dc.typeArticleen_US

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