Burton, Stephanie G.Cowan, Donald A.Woodley, John M.2010-09-292010-09-292002Burton, S., Cowan, D.A., Woodley, J.M. (2002). The search for the ideal biocatalyst. Nature Biotechnology, 20:35-46.http://hdl.handle.net/10566/150While the use of enzymes as biocatalysts to assist in the industrial manufacture of fine chemicals and pharmaceuticals has enormous potential, application is frequently limited by evolution-led catalyst traits. The advent of designer biocatalysts, produced by informed selection and mutation through recombinant DNA technology, enables production of process-compatible enzymes. However, to fully realize the potential of designer enzymes in industrial applications, it will be necessary to tailor catalyst properties so that they are optimal not only for a given reaction but also in the context of the industrial process in which the enzyme is applied.enThis is the author post-print of an article published by Nature Publishing Group.CatalystEnzymes as biocatalystsDesigner biocatalystsProcess-compatible enzymesArticle