Benjeddou, MongiAbrahams, ZainonesaDept. of BiotechnologyFaculty of Science2014-01-292024-05-092011/02/102011/02/102014-01-292024-05-092010https://hdl.handle.net/10566/13279Magister Scientiae - MScThe objective of this study was to develop and validate a six Non-CODIS miniSTR genotyping system and to determine its suitability for forensic casework in South Africa. In Non-CODIS miniSTR genotyping systems, smaller PCR products are amplified and the primers are positioned as close as possible to the repeat region. For this reason, these systems can be valuable in a variety of scenarios including complex paternity cases, missing persons work, and mass fatality disasters.enForensicsMini short tandem repeats (miniSTRs)LociNon-CODIS (NC)Polymerase chain reaction (PCR)DNA sequencingDegraded DNAInternal validationPopulation StudiesAllele frequenciesForensic parametersThesisUniversity of the Western Cape