Chiliza, JessicaLaing, RichardFeeley III, Frank Goodrich2022-07-192022-07-192021Chiliza, J. et al. (2021). Program sustainability post PEPFAR direct service support in the Western Cape, South Africa. PLos One, 16(5), e0251230. 10.1371/journal.pone.02512301932-620310.1371/journal.pone.0251230http://hdl.handle.net/10566/7608Public health practitioners have little guidance around how to plan for the sustainability of donor sponsored programs after the donor withdraws. The literature is broad and provides no consensus on a definition of sustainability. This study used a mixed-methods methodology to assess program sustainability factors to inform donor-funded programs.This study examined 61 health facilities in the Western Cape, South Africa, supported by four PEPFAR-funded non-governmental organizations from 2007 to 2012. Retention in care (RIC) was used to determine health facility performance. Sustainability was measured by comparing RIC during PEPFAR direct service (20072012), to RIC in the post PEPFAR period (2013 to 2015). Forty-three semi-structured in-depth interviews were conducted with key informants. The qualitative data were used to examine how predictor variables were operationalized at a health facility and NGO level.enPublic healthSustainabilityDonor-funded programsHIVWestern CapeArticle