Iwuoha, Emmanuel I.Uhuo, Onyinyechi Vivian2023-01-182024-05-132023-01-182024-05-132022https://hdl.handle.net/10566/14738Philosophiae Doctor - PhDTuberculosis (TB) disease has continued to plague the world, infecting and killing thousands of men, women, and children yearly. Developing countries with limited access to power supply, standard laboratory facilities with special biosafety conditions, and trained medical personnel required for the current diagnostic techniques, experience high TB incidence and deaths yearly. The urgent need to eradicate TB globally can be met with improvement in TB diagnosis. Aptasensor approach to TB diagnosis offers a rapid, user-friendly, robust, highly sensitive, and selective means of detecting biomarkers of TB disease.enAptasensorBiosensorChitosanMethylene blueTuberculosisKesterite-amplified aptameric nanobiosensors for interferon gamma Tuberculosis biomarkerUniversity of the Western Cape