Motswainyana, William M.Onani, Martin O.Madiehe, Abram M.Saibu, MorounkeJacobs, Jeroenvan Meervelt, Luc2014-03-172014-03-172013Imino-quinolyl palladium(II) and platinum(II) complexes: synthesis, characterization, molecular structures and cytotoxic effect. Inorganica Chimica Acta, 400: 197–2020020-1693http://hdl.handle.net/10566/1057Imino-quinolyl ligands L1-L5 were synthesized by condensation reactions and obtained in good yields. Reactions of the ligands with either PdCl2(cod) or K2[PtCl4] gave the corresponding palladium(II) and platinum(II) complexes 1-10 also in good yields. All the compounds were characterized by elemental analysis, IR, 1H and 13C NMR spectroscopy. X-ray crystallography was used to confirm the structures of these compounds. Molecular structures of 3 and 5 showed that the ligands coordinate to the metal centre through the two nitrogen atoms, generating a distorted square planar geometry around the palladium atom. The new complexes exhibited remarkable cytotoxic activities against MCF-7 and HT-29 cancer cell lines.enThis is the author postprint version of an article by Elsevier. The file may be freely used, provided that acknowledgement of the source is given.Imino-quinolylPalladiumPlatinumMolecular structuresCancerCytotoxicityArticle