Perchyonok, TamaraMulder, RiaanGrobler, Sias RenierZhang, Shengmiao2016-09-172016-09-172015Perchyonok, V.T. et al. (2015). Towards bioactive containing restorative materials: from design to testing in vitro approach. Journal of Dentistry, Oral Disorders & Therapy, 3(3): 1-72372-0972http://hdl.handle.net/10566/2410In any repair of a tooth with permanent restorative materials, the interface is always a sensitive region. The appearance of adhesive materials was a great step forward in dealing with the problems of this region and improving the overall performance of the restorations. However, contemporary adhesive materials do have a major disadvantage, namely that their durability is limited, a limitation which often arises due to their inadequate marginal adaptation. Restorative materials in the new era aim to be “bio-active” and long lasting. As part of our continuous interest in developing the novel bioactive containing restorative materials, we evaluated the effect of the additional bio-actives (such as chitosan, β-carotene, guar gum resin and the combination of the materials) to the commercially available flowable restorative materials such as Premise on the volumetric shrinkage, flexural strength, compressive strength, the surface hardness of the “bio-active” containing compositeenOpen Access. Open access means unlimited access and unrestricted use and reuse of all peer-reviewed research articles with the rights to use fully in the digital environment.AntioxidantsFunctional biomaterialsDentin bondingVolumetric change dialometerTooth repairArticle