Ashkani, JahanshahRees, D. J. G.2023-06-052023-06-052016Ashkani, J., & Rees, D. J. G. (2016). A simple, high-throughput modeling approach reveals insights into the mechanism of gametophytic self-incompatibility. Scientific Reports, 6, 34732. https://doi.org/10.1038/srep347322045-2322http://hdl.handle.net/10566/9016Specificity in the GSI response results from the S-haplotype-specific molecular interaction of S-locus F-box (SLF/SFB) and SRNase proteins in the self-incompatibility locus (S-locus). The answer to the question of how these two components of the S-locus (SRNase and SLF/SFB) interact has been gathered from several models. Since there is not enough evidence as to which one is the definitive model, none of them can be ruled out. Despite the identification of interacting protein elements, the mechanism by which SLF/SFB and SRNase interact to differently trigger the self-incompatibility among families and subfamilies remain uncertain. The high-throughput modeling approach demonstrates structural visions into the possible existence of a Collaborative Non-Self Recognition model in apple. These findings postulate several prospects for future investigation providing useful information to guide the implementation of breeding strategies.enBiotechnologyPlant reproductionProteinDiversityArticle