Gray, Glenda E.Laher, FatimaDoherty, TanyaKarim, Salim AbdoolHammer, ScottMascola, JohnBeyrer, ChrisCorey, Larry2018-07-062018-07-062016Gray, G.E. et al. (2016). Which new health technologies do we need to achieve an end to HIV/AIDS? PLOS Biology, 14(3): e10023721544-9173http://dx.doi.org/10.1371/journal.pbio.1002372http://hdl.handle.net/10566/3852In the last 15 years, antiretroviral therapy (ART) has been the most globally impactful lifesaving development of medical research. Antiretrovirals (ARVs) are used with great success for both the treatment and prevention of HIV infection. Despite these remarkable advances, this epidemic grows relentlessly worldwide. Over 2.1 million new infections occur each year, two-thirds in women and 240,000 in children. The widespread elimination of HIV will require the development of new, more potent prevention tools. Such efforts are imperative on a global scale. However, it must also be recognised that true containment of the epidemic requires the development and widespread implementation of a scientific advancement that has eluded us to date—a highly effective vaccine. Striving for such medical advances is what is required to achieve the end of AIDS.enThis is an open access article, free of all copyright, and may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose. The work is made available under the Creative Commons CC0 public domain dedication.Antiretroviral therapy (ART)Antiretrovirals (ARVs)HIVAIDSScientific advancementArticle