Fisher, DJohnson, QMosoval, Faisel2023-07-122024-11-042023-07-122024-11-042003https://hdl.handle.net/10566/17169Magister Scientiae (Medical Bioscience) - MSc(MBS)Certa in medicinal plant extracts have been shown to have a contraceptive effect on male rats (Rajasekaran et al. , 1988) and mice (Kong et al., 1986). A possible site for the mechanism of action has been identified as the testis. The Sertoli cell s within the seminiferous tubules of the teste s are of fundamental importance to the developing sperm. These cells create a unique environment, which, without, would lead to the cessation of spermatogenesis (Gow et al. , 199 9). Know ledge of the Sertoli cell is thus essential in understanding the control of developing germ cells within the seminiferous tubules of the testis.enSertoli cellsMale contraceptivesOleanolic acidSeminiferousElectrophysiologyThesisUniversity of the western cape