Keuler, NicoleOkeyo, IdaThomas, Duran2026-10-122026-10-122026https://hdl.handle.net/10566/25548Introduction: Despite the advances in treatment for drug-resistant tuberculosis (DR-TB) in children, children are still at risk of developing adverse drug reactions (ADRs) during the prolonged treatment process. Monitoring and reporting of ADRs to ensure patient safety is a critical component of pharmacovigilance. The foundation of pharmacovigilance activities relies on ADR reporting by healthcare professionals and patients. However, there are limited studies that have focused on how caregivers of children navigate ADR reporting processes. This study aimed to explore the awareness of caregiver reporting of suspected ADRs in children treated for DR-TB. Methods: A qualitative exploratory study was conducted at Brooklyn Chest Hospital (BCH), a centralised provincial TB institution in Cape Town, between January and June 2025. The study consisted of two phases, phase one included direct observations of healthcare professionals (doctors, nurses, pharmacists) and caregivers for a period of two weeks (Monday to Friday). Phase two included semi-structured interviews with five caregiversenAwarenessCaregiverReportingAdverse drug reactionsChildrenThesis