Furaha AkimanimpayeMillion S. BimerewDeliwe R. Petlhu2025-10-292025-10-292024Akimanimpaye, F., Bimerew, M.S. and Petlhu, D.R., 2024. Challenges experienced by grandparents caring for AIDS orphans in the Western Cape province, South Africa. Health SA Gesondheid, 29, p.2454.https://doi.org/10.4102/hsag.v29i0.2454https://hdl.handle.net/10566/21266Background: There is limited understanding of the difficulties and experiences faced by grandparents who assume the responsibility of caring for AIDS orphans. Aim: The objective of the study was to investigate and depict the difficulties encountered by grandparents who provide care for AIDS orphans in the Western Cape province of South Africa. Setting: The study was conducted in the City of Cape Town Metropolitan and the Overberg municipality. Methods: The study used qualitative approach with an exploratory-descriptive design. A purposive sampling technique was utilised to select 25 grandparents. Semi-structured interviews were conducted, audio-recorded, transcribed verbatim, and analysed thematically using ATLAS.ti, version 7. Results: Financial difficulties, a lack of support, HIV and/or AIDS stigma, and dealing with rebellious teenagers were primary challenges affecting the well-being of grandparents. Conclusion: The study found that while financial challenges were significant, other factors such as poor family support contributed to the decline in the well-being of grandparents caring for AIDS orphans.enHIV and AIDSGrandparentsOrphansSocial supportEmotional supportArticle