Puoane, TMente, ADehghan, M2023-03-292023-03-292022Dehghan, M., Mente, A., Rangarajan, S., Mohan, V., Swaminathan, S., Avezum, A., Lear, S.A., Rosengren, A., Poirier, P., Lanas, F. and Lopez-Jaramillo, P., 2023. Ultra-processed foods and mortality: analysis from the Prospective Urban and Rural Epidemiology study. The American journal of clinical nutrition, 117(1), pp.55-63.00029165http://hdl.handle.net/10566/8701This analysis includes 138,076 participants without a history of CVD between the ages of 35 and 70 y living on 5 continents, with a median follow-up of 10.2 y. We used country-specific validated food-frequency questionnaires to determine individuals’ food intake. We classified foods and beverages based on the NOVA classification into UPFs. The primary outcome was total mortality (CV and non-CV mortality) and secondary outcomes were incident major cardiovascular events. We calculated hazard ratios using multivariable Cox frailty models and evaluated the association of UPFs with total mortality, CV mortality, non-CV mortality, and major CVD events.enFood securityMortalityCardiovascular diseaseEpidemiologyArticle