Dietrich, DaneelOsuafor, Godswill NwabuisiDept. of Medical BioSciencesFaculty of Science2013-12-112024-11-042011/02/232011/02/232013-12-112024-11-042009https://hdl.handle.net/10566/17320Magister Scientiae (Medical Bioscience) - MSc(MBS)Conclusion of this study: These data suggest that 6 weeks of high-fat feeding induces hypertension but does not produce obesity, dyslipidemia and insulin resistance. However, this model may be useful in studying vascular reactivity in hypertension in the absence of insulin resistance.enGlucose tolerance testHigh-fat dietHypertensionInsulin resistanceLipid profileQUICKISprague Dawley ratVascular reactivityVisceral fatÎ- adrenergic responseThesisUniversity of the Western Cape