Roelofse, JamesVenter, J. C.Faculty of Dentistry2013-10-162024-04-152009/10/162009/10/162013-10-162024-04-152007https://hdl.handle.net/10566/10871Magister Scientiae - MScThe purpose of this research project was to assess the safety and efficacy of a combination of drugs for conscious sedation in patients undergoing office-based plastic and reconstructive surgery. A pilot study was done to determine the safety of the co-administration of the drugs used in the sedation technique.enOffice based plastic and reconstructive surgeryIntravenous sedationMidazolamKetaminePropofolAlfentanilLignocaineBupivacaineEpinephrineFrizelle sedation scaleTarget controlled infusionThe safety and efficacy of the propofol/ Alfentanil/ Ketamine-bolus technique in midazolam pre-medicated patients undergoing office based plastic or reconstructive surgeryThesisUniversity of the Western Cape