Christoffels, AlanWamalwa, MarkSouth African National Bioinformatics Institute (SANBI)Faculty of Science2013-07-262024-05-172012/01/052012/01/052013-07-262024-05-172011https://hdl.handle.net/10566/15274Philosophiae Doctor - PhDThis study has successfully identified transcripts differentially expressed in the salivary gland and midgut and provides candidate genes that are critical to response to parasite invasion. Furthermore, an open-source Glossina resource (G-ESTMAP) was developed that provides interactive features and browsing of functional genomics data for researchers working in the field of Trypanosomiasis on the African continent.enTranscriptome annotation systemComparative transcriptomicsAnnotation pipelineDatabaseManual curationOrthoMCLGlossina morsitans morsitansExpressed sequence tagsOpen reading framesThesisUniversity of the Western Cape