Johnson, QuintonMuwanga, CatherineSouth African Herbal Science and Medicine Institute (SAHSMI)Faculty of Science2013-08-272024-10-292007/07/162007/07/162013-08-272024-10-292006https://hdl.handle.net/10566/16336Magister Scientiae - MScIn South Africa, the crude aqueous extract from Hypoxis hemerocallidea is used by AIDS patients to treat opportunistic infections, such as tuberculosis. The rapid emergence of multidrug-resistant tuberculosis, and extreme drug resistant tuberculosis, in recent years, is a major threat to human health. The treatment of TB, nosocomial bacterial infections, and fungal infections is now a clinical challenge, especially in the immuno-compromised individual. There is a dire need for novel antibiotic alternatives with phytotherapies and plant-derived compounds as potentially promising alternatives. The main objective of this study was to investigate the antimycobacterial activity of Hypoxis hemerocallidea, a South African medicinal plant, using Mycobacterium smegmatis.enMateria medicaVegetable - South AfricaMedicinal plantsharmacognosyPlant extractsHypoxidaceaeTherapeutic useAn assessment of Hypoxis hemerocallidea extracts, and actives as natural antibiotic, and immune modulation phytotherapiesThesisUniversity of the Western Cape