Ibrakaw, Abobaker S.Omoruyi, Sylvester I.Ekpo, Okobi E.2020-12-072020-12-072020Ibrakaw, A. S. et al. (2020). Neuroprotective Activities of Boophone haemanthoides (Amaryllidaceae) Extract and Its Chemical Constituents. Molecules (Basel, Switzerland), 25(22)1420-3049https://doi.org/10.3390/molecules25225376http://hdl.handle.net/10566/5482Parkinson’s disease (PD) is a neurodegenerative condition that progresses as age increases, and some of its major symptoms include tremor and postural and movement-related difficulties. To date, the treatment of PD remains a challenge because available drugs only treat the symptoms of the disease or possess serious side effects. In light of this, new treatment options are needed; hence, this study investigates the neuroprotective effects of an organic Boophone haemanthoides extract (BHE) and its bioactive compounds using an in vitro model of PD involving the toxin 1-methyl-4-phenylpyridinium (MPP+) and SH-SY5Y neuroblastoma cells.enAmaryllidaceaeBoophone haemanthoidesAlkaloids; terpenoidsParkinson’s diseaseNeuroprotectionArticle