Nyongesa, Christine Khanili2024-11-012024-11-012023https://hdl.handle.net/10566/16999Dentine sensitivity, hinders oral hygiene practices and limits consumption of specific foods and drinks. Studies have shown that, the severity of dentine sensitivity is related to the permeability of dentine tubules such that the more permeable the tubule is the higher the degree of sensitivity. Hydroxyapatite is one of the components known to block dentine tubules to reduce their permeability. The use of eggshells in deriving nano hydroxyapatite is an important approach as it also contributes to organic waste management. The purpose of this study was to assess and compare the effectiveness of organic nano hydroxyapatite derived from eggshells on dentine tubules permeability. This is an in vitro study, in which specimens of 72 human tooth dentine material were sectioned to thickness of 120, 250, 350, 500, 750, 1000 micrometers. The specimens were then exposed to four groups of treatment including deionized water, Sensodyne Sensitivity and Gum toothpaste, Colgate toothpaste and organic derived nanohydroxyapatite derived from eggshells.enDentine tubules permeabilityDesensitizing agents’Hydraulic conductivityHydrodynamic theoryOrganic derived Nano hydroxyapatiteThesis