Esau, MichelleMfeketho, Mziwoxolo2020-02-252024-05-032020-02-252024-05-032019https://hdl.handle.net/10566/12921Magister Administrationis - MAdminIn this study, new solid supramolecular derivatised forms of bis(adamantine-1-aminium) carbonate (ADTCO3) were prepared. ADTCO3 is a derivative of amantadine used for Parkinson’s disease and has antiviral properties against influenza-A, dengue fever and pharmacological activity towards Parkinson’s disease. The new forms prepared were polymorphic and co-crystal forms of ADTCO3. Polymorphism is a phenomenon where the ability of a substance to exist in two or more crystalline forms occurs when crystallised under different conditions and co-crystallization is the process of formation of multicomponent crystals of a drug substance.enCorrectional system officialsPrisonsOvercrowdingSouth AfricaDepartment of JusticeDepartment of correctional servicesUniversity of the Western Cape