Moabelo KoenaMeyer MervinTsaulwayo NokwandaXulu Bheki2025-09-042025-09-042025Tsaulwayo, N., Moabelo, K. L., Meyer, M., & Ojwach, S. O. (2025). Investigation of the coordination chemistry, biomolecular interactions and cytotoxicity of heterocyclic carboxamide manganese(II) complexes. European Journal of Inorganic Chemistry. https://doi.org/10.1002/ejic.202500234https://hdl.handle.net/10566/20834For the past few decades, platinum-based compounds notably cisplatin have been the most commonly used in metal-based anti-cancer treatment.[1,2] Despite the success of cisplatin, it has several drawbacks such as side effects, poor solubility, and acquired drug resistance, thus limiting its efficacy. [3,4] These negative attributes of cisplatin have germinated research interests in the design and development of alternative nonplatinum metallo-drugs such as ruthenium, iridium, osmium, palladium, and manganese. [5–7] Compared to the extensive reports on noble metals such as ruthenium and palladium, there are few reports on these of manganese compounds as anticancer agents. [8]enReactions of ligands 5-methyl-NN-(N-(pyridin-2-ylmethyl)pyrazine-2-carboxamideN-(quinolin-8-yl)picolinamideN-(quinolin-8-yl)quinoline-2-carboxamideSolid state structuresArticle