Mazloum, AliVan Schalkwyk, AntoinetteChernyshev, Roman2022-09-192022-09-192022Mazloum, A. et al. (2022). Genetic characterization of the central variable region in African swine fever virus isolates in the Russian federation from 2013 to 2017. Pathogens, 11(8), 919. https://doi.org/10.3390/pathogens110809192076-0817https://doi.org/10.3390/pathogens11080919http://hdl.handle.net/10566/7903African swine fever virus (ASFV), classified as genotype II, was introduced into Georgia in 2007, and from there, it spread quickly and extensively across the Caucasus to Russia, Europe and Asia. The molecular epidemiology and evolution of these isolates are predominantly investigated by means of phylogenetic analysis based on complete genome sequences. Since this is a costly and timeconsuming endeavor, short genomic regions containing informative polymorphisms are pursued and utilized instead. In this study, sequences of the central variable region (CVR) located within the B602L gene were determined for 55 ASFV isolates submitted from 526 active African swine fever (ASF) outbreaks occurring in 23 different regions across the Russian Federation (RF) between 2013 and 2017. The new sequences were compared to previously published data available from Genbank, representing isolates from Europe and Asia. The sequences clustered into six distinct groups.enSwine fever virusAfricaPublic healthBiotechnologyDomestic pigsArticle