Stephen, L.X.G.Tareq, Abu SalehDept. of Oral Medicine and PeriodonticsFaculty of Science2013-10-242024-04-162009/10/262009/10/262013-10-242024-04-162007https://hdl.handle.net/10566/11072Magister Scientiae - MScPeriodontitis is a bacterially induced chronic inflammatory disease that destroys the supporting tissues of teeth. Clinical observations and experimental evidence indicates that there is a genetic influence of risk factors for periodontitis. A specific pattern of IL-1 polymorphisms (known as the composite IL-1 genotype) has been found to influence the severity of chronic periodontitis. The objective of this study was to evaluate the association between the IL-1 gene polymorphisms and the severity of periodontal disease in a selected Xhosa ppopulation of South africa.enPeriodontal diseasePeriodonticsThesisUniversity of the Western Cape