Syce, James A.Mulubwe, Ngosa.Faculty of Science2013-11-212024-05-152009/11/112009/11/112013-11-212024-05-152007https://hdl.handle.net/10566/15192Magister Pharmaceuticae - MPharmThe specific objectives of this study were to investigate whether Artemisia Afra, Leonotis leonorous and Mentha Longiflora have PDE 4 inhibitory activity, to determine and compare the levels of the total phenolic compunds , total and individual flavanoids, especially luteolin and hesperetin, in the three plants and finally, to determine if there was a correlation between the PDE inhibitory activity and the levels of flavanoids or phenolic compounds in the plants. It was hypothesized that the plants with higher levels of total flavonoid and/or aglycone luteolin and/or hesperetin had higher PDE inhibitory activity.enMedicinal PlantsThesisUniversity of the Western Cape