Ismaila, RajiKenechukwu, ObikezeMugabo, Pierre2016-01-062016-01-062015Ismaila, R. et al. (2015). Potential beneficial effects of Tulbaghia violacea William Henry Harvey (Alliaceae) on cardiovascular system - A review. Tropical Journal of Pharmaceutical Research, 14 (6): 1111-11171596-9827http://hdl.handle.net/10566/2048Tulbaghia violacea William Henry Harvey (Harv. Alliaceae) is a small bulbous herb belonging to the family Alliaceae. It is used in South Africa to treat fever, colds, asthma, paralysis, and hypertension. Meanwhile, cardiovascular disease accounts for about 30 % of total global death, with most of these deaths occurring in low and middle-income countries. Furthermore, people in low-income countries are still largely dependent on plants in their surroundings for both prophylaxis and treatment of diseases, partly due to limited access to and cost of pharmaceuticals, and folkloric evidence of the potency of medicinal plants and/or local belief systems. Therefore, the present review aims to proffer possible ways by which T. violacea may improve cardiovascular outcomes. An extensive and systematic review of the literature was carried out, and relevant findings presented in this review. There is evidence that T. violacea may modulate the renin-angiotensin system, the autonomic nervous system, oxidative stress and haemostasis, with resultant protection of the cardiovascular system in both health and disease.enThe Pharmacotherapy Group grants authors the right to use all or part of the Article, including the Pharmacotherapy Group-prepared version without revision or modification, on the author(s)’ web home page or employer’s website and to make copies of all or part of the Article for the author(s)’ and/or the employer’s use for lecture or classroom purposes.Tulbaghia violaceaHypertensionRenin-angiotensin aldosterone systemBlood pressureCardiovascular diseaseAutonomic nervous systemOxidative stressHaemostasisTreatmentTulbaghia violacea William Henry Harvey (Harv. Alliaceae)Article