Gunes, SezginSengupta, PallavHenkel, RalfAlguraigari, AabedSinigaglia, Mariana MarquesKayal, MalikJoumah, AhmadAgarwal, Ashok2018-11-052018-11-052018Gunes, S. et al. (2018). Microtubular dysfunction and male infertility. The World Journal of Men's Health, 2018.2287-4208https://doi.org/10.5534/wjmh.180066http://hdl.handle.net/10566/4180Microtubules are the prime component of the cytoskeleton along with microfilaments. Being vital for organelle transport and cellular divisions during spermatogenesis and sperm motility process, microtubules ascertain functional capacity of sperm. Also, microtubule based structures such as axoneme and manchette are crucial for sperm head and tail formation. This review (a) presents a concise, yet detailed structural overview of the microtubules, (b) analyses the role of microtubule structures in various male reproductive functions, and (c) presents the association of microtubular dysfunctions with male infertility. Considering the immense importance of microtubule structures in the formation and maintenance of physiological functions of sperm cells, this review serves as a scientific trigger in stimulating further male infertility research in this direction.enThis is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.AxonemeMale infertilityKartagener syndromeMicrotubule-associated proteinsArticle