Ludidi, NdikoGehring, Chris2023-03-012023-03-012003Ludidi, N., & Gehring, C. (2003). Identification of a novel protein with guanylyl cyclase activity in Arabidopsis thaliana. Journal of Biological Chemistry, 278 (8) ,6490-6494. https://doi.org/10.1074/jbc.M2109832001083-351Xhttps://doi.org/10.1074/jbc.M210983200http://hdl.handle.net/10566/8488Guanylyl cyclases (GCs) catalyze the formation of the second messenger guanosine 3 ,5 -cyclic monophos- phate (cGMP) from guanosine 5 -triphosphate (GTP). While many cGMP-mediated processes in plants have been reported, no plant molecule with GC activity has been identified. When the Arabidopsis thaliana genome is queried with GC sequences from cyanobacteria, lower and higher eukaryotes no unassigned proteins with sig- nificant similarity are found. However, a motif search of the A. thaliana genome based on conserved and func- tionally assigned amino acids in the catalytic center of annotated GCs returns one candidate that also contains the adjacent glycine-rich domain typical for GCs.enBiotechnologyProteinArabidopsis thalianaGuanylyl cyclasesArticle