Holmes, Halyde Villiers, Carl2025-02-212025-02-212024https://hdl.handle.net/10566/20098Periodontitis is a chronic inflammatory disease resulting in progressive destruction of the tissues supporting the teeth (Hajishengallis and Chavakis, 2021). There is ever increasing evidence in the literature of the link between periodontitis and systemic diseases. The periodontal disease phenotype is characterised by an exaggerated, ineffective, and persistent inflammation of the connective tissues that supports the teeth, which ultimately results in tissue destruction and CAL (Meyle and Chapple, 2015). The main goal of periodontal treatment is to establish acceptable infection control by reducing the microbial load below individual threshold levels of inflammation (Suvan et al., 2020). Anaemia is a worldwide health problem that affects both the developed and developing world with far ranging effects on health of people including socio-economic burdens (Domenica Cappellini and Motta, 2015). Anaemia of chronic disease (ACD) is also known as anaemia of inflammation. Globally, this is the second most prevalent form of anaemia. ACD is usually mild, and the focus should be management of the underlying condition.enAnaemiaClinical attachment lossHaemoglobinPeriodontal diseaseRed blood cellsThesis