Intervertebral disc degenerative disease in South Africa: a case-control analysis of selected gene variants

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Date

2024

Journal Title

Journal ISSN

Volume Title

Publisher

Springer Nature

Abstract

Intervertebral disc (IVD) degenerative disease is a multifactorial disease for which genetics plays an integral role. Several genes, and their variants, associated with the development and progression of IVD degenerative disease have been identified. While several studies have investigated these genes in Asian and European populations, no available evidence exists for the South African population. Therefore, this study aimed to investigate these parameters.

Description

Keywords

Intervertebral disc degenerative disease, Single nucleotide polymorphism, Genotype, Allele, South Africa

Citation

Pearce, K., Less, S., Liebenberg, A.W. and Benjeddou, M., 2024. Intervertebral disc degenerative disease in South Africa: a case-control analysis of selected gene variants. Molecular Biology Reports, 51(1), p.992.